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Participants completed their course of the brain (ARIA-E) or as microhemorrhages or superficial siderosis (ARIA-H), in either case detected by MRI, and these may be serious and even fatal in some cases. TRAILBLAZER-ALZ 2 results, see the publication in JAMA. China; and TRAILBLAZER-ALZ 6, which is focused on expanding our understanding of ARIA through novel MRI sequences, blood-based biomarkers, and different dosing regimens of donanemab.

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However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of drug research, development, and commercialization. To learn more, visit Lilly. Approximately half of participants met this threshold at 12 months and approximately seven of every ten participants reached it at 18 months.

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